Opioid-Overdose Reduction Continuum of Care Approach (ORCCA) Practice Guide

This guide includes (1) a menu of evidence-based practices spanning the continuum of care to reduce opioid overdose deaths and (2) real-word tips for implementing the evidence-based strategies. This guide was developed for the Substance Abuse and Mental Health Services Administration (SAMHSA) Technology Transfer Centers (TTC) program.


  • Tips for Data-Driven Strategy Selection
  • Evidence-based strategies to
    • Increase Opioid Overdose Prevention Education and Naloxone Distribution
    • Enhance the Delivery of MOUD
    • Improve Prescription Opioid Safety
  • Case Examples of Communities Implementing Strategies